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Browsing by Author "García, Elisabet"

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Anti-MPER antibodies with heterogeneous neutralization capacity are detectable in most untreated HIV-1 infected individuals

Molinos-Albert, Luis M.; Carrillo, Jorge; Curriu, Marta; Rodríguez de la Concepción, Maria L.; Marfil, Sílvia; García, Elisabet; Clotet, Bonaventura; Blanco, Julià (Biomed central, 2014)

Background The MPER region of the HIV-1 envelope glycoprotein gp41 is targeted by broadly neutralizing antibodies. However, the localization of this epitope in a hydrophobic environment seems to hamper the elicitation of ...
gp120/CD4 Blocking Antibodies Are Frequently Elicited in ART-naive Chronically HIV-1 Infected Individuals

Carrillo, Jorge; Molinos-Albert, Luis M.; Rodríguez de la Concepción, Maria L.; Marfil, Sílvia; García, Elisabet; Clotet, Bonaventura; Blanco, Julià (Mary Ann Liebert, Inc, 2014)
Gp120/CD4 blocking antibodies are frequently elicited in ART-naïve chronically HIV-1 infected individuals

Carrillo, Jorge; Molinos-Albert, Luis M.; Rodríguez de la Concepción, Maria L.; Marfil, Sílvia; García, Elisabet; Derking, Ronald; Sanders, Rogier W.; Clotet, Bonaventura; Blanco, Julià (Plos One, 2015)

Antibodies with the ability to block the interaction of HIV-1 envelope glycoprotein (Env) gp120 with CD4, including those overlapping the CD4 binding site (CD4bs antibodies), can protect from infection by HIV-1, and their ...
Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif

Molinos-Albert, Luis M.; Bilbao, Eneritz; Agulló, Luis; Marfil, Sílvia; García, Elisabet; Rodríguez de la Concepción, Maria L.; Izquierdo Useros, Nuria; Vilaplana, Cristina; Nieto-Garai, Jon A.; Contreras, F. Xabier; Floor, Martin; Cardona, Pere J.; Martinez Picado, Francisco Javier; Clotet, Bonaventura; Villà-Freixa, Jordi; Lorizate, M.; Carrillo, Jorge; Blanco, Julià (Nature Publishing Group, 2017)

The HIV-1 gp41 Membrane Proximal External Region (MPER) is recognized by broadly neutralizing antibodies and represents a promising vaccine target. However, MPER immunogenicity and antibody activity are influenced by ...

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Browsing by Author "García, Elisabet"

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