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Consulteu Articles per autor "Calle, M. Luz"

Consulteu Articles per autor "Calle, M. Luz"

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  • A dynamic model for the risk of bladder cancer progression
    Porta, Núria; Calle, M. Luz; Malats i Riera, Núria; Gómez, Guadalupe (Wiley, 2012)
    We propose a multistate modeling approach to describe the observed evolution of patients diagnosed with nonmuscle- invasive bladder cancer. On the basis of data from the Spanish Bladder Cancer/EPICURO study, we adjust a ...
  • A new PDAC mouse model originated from iPSCs-converted pancreatic cancer stem cells (CSCcm)
    Sanchez Calle, Anna; Nair, Neha; KoKo Oo, Aung; Prieto-Vila, Marta; Koga, Megumi; Cahya Khayrani, Apriliana; Hussein, Maram; Hurley, Laura; Vaidyanath, Arun; Seno, Akimasa; Iwasaki, Yoshiaki; Calle, M. Luz; Kasai, Tomonari; Seno, Masaharu (eCentury Publishing Corporation, 2016)
    Pancreatic ductal adenocarcinoma (PDAC) is the most representative form of pancreatic cancers. PDAC solid tumours are constituted of heterogeneous populations of cells including cancer stem cells (CSCs), differentiated ...
  • A Semiparametric hierarchical method for a regression model with an interval-censored covariate
    Calle, M. Luz; Gómez, Guadalupe (Blackwell Publishers, 2005)
    A Bayesian framework is proposed for analysing regression models in which one of the covariates is interval-censored. Such a situation was encountered in an AIDS clinical trial in which the goal was to examine the ...
  • Application of Multi-SNP Approaches Bayesian LASSO and AUC-RF to Detect Main Effects of Inflammatory-Gene Variants Associated with Bladder Cancer Risk
    López de Maturana, Evangelina; Ye, Yuanging; Calle, M. Luz; Rothman, Nathaniel; Urrea Gales, Víctor; Kogevinas, Manolis; Petrus, Sandra; Chanock, Stephen; Tardón, Adonina; García-Closas, Montserrat; González-Neira, Anna; Vellalta, Gemma; Carrato, Alfredo; Navarro, Arcadi; Lorente-Galdós, Belén; Silverman, Debra T.; Real, Francisco X.; Wu, Xifeng; Malats i Riera, Núria (Public Library of Science, 2013)
    The relationship between inflammation and cancer is well established in several tumor types, including bladder cancer. We performed an association study between 886 inflammatory-gene variants and bladder cancer risk in ...
  • AUC-RF: A New Strategy for Genomic Profiling with Random Forest
    Calle, M. Luz; Urrea Gales, Víctor; Boulesteix, Anne-Laure; Malats i Riera, Núria (Karger, 2011)
    Objective: Genomic profiling, the use of genetic variants at multiple loci simultaneously for the prediction of disease risk, requires the selection of a set of genetic variants that best predicts disease status. The ...
  • Árboles de clasificación y regresión en la investigación biomédica
    Calle, M. Luz; Sánchez Espigares, Josep A. (Doyma, 2007)
  • Bayesian survival analysis modeling applied to sensory shelf life of foods
    Calle, M. Luz; Hough, Guillermo; Curia, Ana; Gómez, Guadalupe (Elsevier, 2006)
    Data from sensory shelf-life studies can be analyzed using survival statistical methods. The objective of this research was to introduce Bayesian methodology to sensory shelf-life studies and discuss its advantages in ...
  • An efficient algorithm to perform multiple testing in epistasis screening
    Van Lishout, François; Mahachie John, Jestinah M.; Gusareva, Elena S.; Urrea Gales, Víctor; Cleynen, Isabelle; Théâtre, Emilie; Charloteaux, Benoït; Calle, M. Luz; Wehenkel, Louis; Van Steen, Kristel (Biomed Central, 2013)
    Background: Research in epistasis or gene-gene interaction detection for human complex traits has grown over the last few years. It has been marked by promising methodological developments, improved translation efforts ...
  • FAM-MDR: a flexible family-based multifactor dimensionality reduction technique to detect epistasis using related individuals
    Cattaert, Tom; Urrea Gales, Víctor; Naj, Adam C.; De Lobel, Lizzy; De Wit, Vanessa; Fu, Mao; Mahachie John, Jestinah M.; Shen, Haiqing; Calle, M. Luz; Ritchie, Marylyn D.; Edwards, Todd L.; Van Steen, Kristel (04-2010)
    We propose a novel multifactor dimensionality reduction method for epistasis detection in small or extended pedigrees, FAM-MDR. It combines features of the Genome-wide Rapid Association using Mixed Model And Regression ...
  • Frequentist and Bayesian approaches for interval-censored data
    Gómez, Guadalupe; Calle, M. Luz; Oller, Ramon (Springer, 2004)
    Interval censoring appears when the event of interest is only known to have occurred within a random time interval. Estimation and hypothesis testing procedures for interval-censored data are surveyed. We distinguish ...
  • Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
    Guey, Lin T.; García-Closas, Montserrat; Murta-Nascimento, Cristiane; Lloreta, Josep; Palencia, Laia; Kogevinas, Manolis; Rothman, Nathaniel; Vellalta, Gemma; Calle, M. Luz; Marenne, Gaëlle; Tardón, Adonina; Carrato, Alfredo; García Closas, Reina; Serra, Consol; Silverman, Debra T.; Chanock, Stephen; Real, Francisco X.; Malats i Riera, Núria (Elsevier, 2010)
    Background: Clinical, pathologic, and molecular evidence indicate that bladder cancer is heterogeneous with pathologic/molecular features that define distinct subphenotypes with different prognoses. It is conceivable ...
  • Genetic Variation in the TP53 Pathway and Bladder Cancer Risk. A Comprehensive Analysis
    Pineda, S.; Milne, R.L.; Calle, M. Luz; Rothman, Nathaniel; López de Maturana, Evangelina; Herranz, J.; Kogevinas, Manolis; Chanock, Stephen; Tardón, Adonina; Márquez, M.; Guey, Lin T.; García-Closas, Montserrat; Lloreta, Josep; Baum, E.; González-Neira, Anna; Carrato, Alfredo; Navarro, Arcadi; Silverman, Debra T.; Real, Francisco X.; Malats i Riera, Núria (Public Library of Science, 2014)
    Introduction: Germline variants in TP63 have been consistently associated with several tumors, including bladder cancer, indicating the importance of TP53 pathway in cancer genetic susceptibility. However, variants in ...
  • Global adaptive rank truncated product method for gene-set analysis in association studies
    Vilor Tejedor, Natàlia; Calle, M. Luz (Wiley, 2014)
    Gene set analysis (GSA) aims to assess the overall association of a set of genetic variants with a phenotype and has the potential to detect subtle effects of variants in a gene or a pathway that might be missed when ...
  • Improving strategies for detecting genetic patterns of disease susceptibility in association studies
    Calle, M. Luz; Urrea Gales, Víctor; Vellalta, Gemma; Malats i Riera, Núria; Steen, K.V. (Wiley InterScience, 2008)
    The analysis of gene interactions and epistatic patterns of susceptibility is especially important for investigating complex diseases such as cancer characterized by the joint action of several genes. This work is motivated ...
  • Interval censoring: identifiability and the constant-sum property
    Oller, Ramon; Gómez, Guadalupe; Calle, M. Luz (Oxford University Press, 2007)
    The constant-sum property given in Oller et al. (2004) for censoring models justifies the use of a simplified likelihood to obtain the nonparametric maximum likelihood estimator of the lifetime distribution. In this paper ...
  • Interval censoring: model characterizations for the validity of the simplified likelihood
    Oller, Ramon; Gómez, Guadalupe; Calle, M. Luz (Société statistique du Canada, 2004)
    En analyse de durées de vie, le problème de la censure par intervalle a généralement été traité par des méthodes vraisemblantistes. Comme la vraisemblance est complexe, on suppose souvent que les mécanismes de censure ...
  • mbmdr: an R package for exploring gene–gene interactions associated with binary or quantitative traits
    Calle, M. Luz; Urrea Gales, Víctor; Malats i Riera, Núria; Van Steen, Kristel (Oxford University Press, 2010)
    Summary: We describe mbmdr, an R package for implementing the model-based multifactor dimensionality reduction (MB-MDR) method. MB-MDR has been proposed by Calle et al. as a dimension reduction method for exploring ...
  • Model-Based Multifactor Dimensionality Reduction for detecting epistasis in case–control data in the presence of noise
    Cattaert, Tom; Calle, M. Luz; Dudek, Scott M.; Mahachie John, Jestinah M.; Van Lishout, François; Urrea Gales, Víctor; Ritchie, Marylyn D.; Van Steen, Kristel (Blackwell, 2011)
    Analyzing the combined effects of genes and/or environmental factors on the development of complex diseases is a great challenge from both the statistical and computational perspective, even using a relatively small number ...
  • Nonparametric Bayesian estimation from interval-censored data using Monte Carlo methods
    Calle, M. Luz; Gómez, Guadalupe (Elsevier, 2001)
    We study the estimation of the survival function based on interval-censored data from a nonparametric Bayesian point of view. Interval censoring arises when the time variable of interest cannot be directly observed and ...
  • Number of consumers necessary for shelf life estimations based on survival analysis statistics
    Hough, Guillermo; Calle, M. Luz; Serrat Jurado, Carles; Curia, Ana (Elsevier, 2007)
    Survival analysis statistics have been used to estimate shelf life of foods based on consumers’ acceptance or rejection of samples with different storage times. The interval censored nature of the data does not allow ...

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