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Browsing by Author "Yoshino, Takayuki"

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Analysis of angiogenesis biomarkers for ramucirumab efficacy in patients with metastatic colorectal cancer from RAISE, a global, randomized, double-blind, phase III study

Tabernero, Josep; Hozak, R.R.; Yoshino, Takayuki; Cohn, A.L.; Obermannova, R.; Bodoky, G.; Garcia Carbonero, R.; Ciuleanu, T.E.; Portnoy, D.C.; Prausova, J.; Van Cutsem, Eric (Elsevier, 2018)

Background: The phase III RAISE trial (NCT01183780) demonstrated that the vascular endothelial growth factor (VEGF) receptor (VEGFR)-2 binding monoclonal antibody ramucirumab plus 5-fluororuracil, leucovorin, and irinotecan ...
Binimetinib Encorafenib and Cetuximab Triplet Therapy for Patients With BRAF V600E-Mutant Metastatic Colorectal Cancer: Safety Lead-In Results From the Phase III BEACON Colorectal Cancer Study

Van Cutsem, Eric; Huijberts, Sanne; Grothey, Axel; Yaeger, Rona; Cuyle, Pieter-Jan; Elez, Elena; Fakih, Marwan; Montagut, Clara; Peeters, Marc; Yoshino, Takayuki; Kopetz, Scott; Tabernero, Josep (Lippincott Williams & Wilkins, 2019)

To determine the safety and preliminary efficacy of selective combination targeted therapy for BRAF V600E-mutant metastatic colorectal cancer (mCRC) in the safety lead-in phase of the open-label, randomized, three-arm, ...
Encorafenib plus cetuximab as a new standard of care for previously treated BRAF V600E-mutant metastatic colorectal cancer: Updated survival results and subgroup analyses from the BEACON study

Tabernero, Josep; Grothey, Axel; Van Cutsem, Eric; Wasan, Harpreet; Yoshino, Takayuki; Desai, Jayesh; Ciardiello, Fortunato; Loupakis, Fotio; Hong, Yong Sang (American Society of Clinical Oncology, 2021)

PURPOSE BEACON CRC evaluated encorafenib plus cetuximab with or without binimetinib versus investigators' choice of irinotecan or FOLFIRI plus cetuximab in patients with BRAF V600E-mutant metastatic colorectal cancer (mCRC), ...

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Browsing by Author "Yoshino, Takayuki"

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