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Browsing by Author "Llibre, Josep M."

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Different Plasma Markers of Inflammation Are Influenced by Immune Recovery and cART Composition or Intensification in Treated HIV Infected Individuals

Massanella, Marta; Ouchi, Dan; Marfil, Sílvia; Llibre, Josep M.; Puertas, M.C.; Buzon, Maria J.; Richman, Douglas D.; Orna, Elisa; Stevenson, Mario; Gatell, J.M.; Domingo, Pere; Negredo, Eugenia; Martinez Picado, Francisco Javier; Clotet, Bonaventura; Blanco, Julià (Public Library of Science, 2014)

Abstract Background HIV-1 infection increases plasma levels of inflammatory markers. Combination antiretroviral therapy (cART) does not restore inflammatory markers to normal levels. Since intensification of cART ...
Effect of Maraviroc Intensification on HIV-1-Specific T Cell Immunity in Recently HIV-1-Infected Individuals

Kawana-Tachikawa, A.; Llibre, Josep M.; Bravo, Isabel; Escrig, R.; Mothe, B.; Puig, Jordi; Puertas, M.C.; Martinez Picado, Francisco Javier; Blanco, Julià; Manzardo, C.; Miró, J.M.; Iwamoto, A.; Pozniak, A.L.; Gatell, J.M.; Clotet, Bonaventura; Brander, Christian (Public Library of Science, 2014)

Background The effect of maraviroc on the maintenance and the function of HIV-1-specific T cell responses remains unknown. Methods Subjects recently infected with HIV-1 were randomized to receive anti-retroviral ...
Effectiveness of a Treatment Switch to Nevirapine plus Tenofovir and Emtricitabine (or Lamivudine) in Adults with HIV-1 Suppressed Viremia

Llibre, Josep M.; Bravo, Isabel; Ornelas, Arelly; Santos, José R.; Puig, Jordi; Martín Iguacel, Raquel; Paredes, Roger; Clotet, Bonaventura (Plos One, 2015)

Background Switching subjects with persistently undetectable HIV-1 viremia under antiretroviral treatment (ART) to once-daily tenofovir/emtricitabine (or lamivudine) + nevirapine is a cost-effective and well-tolerated ...
Hidden costs of antiretroviral treatment: the public health efficiency of drug packaging

Andreu-Crespo, A.; Llibre, Josep M.; Cardona-Peitx, G.; Sala-Piñol, F.; Clotet, Bonaventura; Bonafont-Pujol, X. (Dove Medical Press, 2015)

While the overall percentage of unused antiretroviral medicines returned to the hospital pharmacy is low, their cost is quite high. Adverse events, treatment failure, pharmacokinetic interactions, pregnancy, or treatment ...
Monotherapy with boosted PIs as an ART simplification strategy in clinical practice

Santos, José R.; Llibre, Josep M.; Berrio-Galan, Daniel; Bravo, Isabel; Miranda, Cristina; Pérez-Alvarez, Susana; Pérez Alvarez, Núria; Paredes, Roger; Clotet, Bonaventura; Moltó, José (Oxford University Press, 2015)

Background: Data on the efficacy of simplifying therapy using darunavir/ritonavir and lopinavir/ritonavir monotherapy in clinical practice remain limited. Methods: A retrospective single-centre study including patients ...
Perfil de resistencias y barrera genética de dolutegravir

Llibre, Josep M.; Clotet, Bonaventura (Elsevier, 2015)

Dolutegravir tiene un perfil de resistencias significativamente distinto al de anteriores inhibidores de la integrasa. Es activo in vitro frente a VIH-1 (virus de la inmunodeficiencia humana-1) portador de cualquier mutación ...
Prevalence of Ischemic Heart Disease and Management of Coronary Risk in Daily Clinical Practice: Results from a Mediterranean Cohort of HIV-Infected Patients

Echeverria, Patricia; Domingo, Pere; Llibre, Josep M.; Gutierrez, Mar; Mateo, Gracia; Puig, Jordi; Bonjoch, Anna; Pérez Alvarez, Núria; Sirera, Guillem; Clotet, Bonaventura; Negredo, Eugenia (Hindawi Publishing Corporation, 2014)

There are conflicting data on the prevalence of coronary events and the quality of the management of modifiable cardiovascular risk factors (CVRF) inHIV-infected patients. Methods.We performed a retrospective descriptive ...
The Lipid-Lowering Effect of Tenofovir/ Emtricitabine: A Randomized, Crossover, Double-Blind, Placebo-Controlled Trial

Santos, José R.; Saumoy, M.; Curran, Adrian; Bravo, Isabel; Llibre, Josep M.; Navarro, Jordi; Estany, Carla; Podzamczer Palter, Daniel; Ribera, Esteban; Negredo, Eugenia; Clotet, Bonaventura; Paredes, Roger (Oxford University Press, 2015)

Background. It is unknown if tenofovir disoproxil fumarate (TDF), which is often coformulated with the lipidneutral emtricitabine (FTC), has a lipid-lowering effect. Methods. We performed a randomized, crossover, ...

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Browsing by Author "Llibre, Josep M."

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