Inicio
→
Docència
→
Treballs de l'alumnat
→
Treballs de Fi de Màster
→
Màster Universitari en Anàlisi de Dades Òmiques
→
Listar Màster Universitari en Anàlisi de Dades Òmiques por título

Listar Màster Universitari en Anàlisi de Dades Òmiques por título

Mostrando ítems 55-74 de 78

Lipid metabolism as a therapeutic vulnerability in medulloblastoma

Escudero Monreal, Laura (01-09-2023)

Medulloblastoma (MB) is the most common malignant brain tumor in children and presents a varied prognosis, with some patients succumbing to the disease and survivors presenting neurotoxic sequelae from treatment. ...
Local assortativity as a chromatin network analysis tool

García Prieto, Carlos Antonio (09-2018)

Using network analysis in the study of chromatin 3D structure has proved to be a powerful and useful approach. In order to determine which factors bound to DNA might play a role in establishing these 3D chromatin structure, ...
Long-term health risks of hyperinsulinaemic androgen excess appear in adolescence with serum markers of oxidative stress and impaired HDL maturation through oxidation of methionine residues in apolipoprotein A1

Samino Gené, Sara (09-2014)
Machine learning methods in personalized medicine: application to genomic data in Alzheimer's disease

Ballestà López, Mireia (09-2018)

The main goal of this project is to validate and compare machine learning methods to perform GWAS analysis. This study worked with genomic data on Alzheimer’s disease (AD). The data obtained was imputed by the Michigan ...
Machine learning-based gene expression signature for classification of endocrine therapy sensitivity in ER+ breast cancer patients

Flamen, Giles (10-09-2023)

Abstract: Endocrine therapy (ET) combined with cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) is the standard treatment for metastatic estrogen receptor-positive (ER+) breast cancer. However, not all patients require this ...
mCSEA: Identification of subtle differential methylation in predefined regions. Studying the epigenomics of fetal growth disorders

Martorell Marugán, Jordi (09-2017)

DNA methylation is the most studied epigenetic mark. It affects gene expression and has an im-portant role in several disorders. EWAS are performed to find associations between DNA methylation alterations and a given ...
Methylation Data Analysis Associated with Alzheimer’s Disease

Mosquera, José Luis (09-2015)

Alzheimer disease (AD) is associated with distinctive changes in DNA methylation patterns. DNA methylation is a chemical modification that is involved in gene silencing. These modifications give rise to heritable changes ...
Modelling GPCR homodimers using molecular dynamics simulations

García Recio, Adrián (17-09-2018)

G protein-coupled receptors (GPCRs) form the largest family of membrane proteins in the human genome and are involved in important physiological functions. Therefore, they are very attractive pharmacological targets for ...
Novel transcript discovery in yeast using sequencing reads from Oxford Nanopore Technologies in comparison to Next Generation Sequencing

Lloret-Villas, Audald (09-2018)

The advent of Oxford Nanopore Technologies is expected to play a pivotal role in near future sequencing studies. Omics data analysis and related processes, currently bound to Next Generation Sequencing, can be now ...
Omic characterization of melanoma for the identification of potential biomarkers in response to immune checkpoint inhibitors

Jiménez-Martínez, Víctor (08-2022)

Cutaneous Malignant Melanoma (CMM) is a rapidly increasing malignancy for which immune check-point inhibition has proved efficient in inducing an anti-cancer immune response. However, not all pa-tients are able to benefit ...
Oral/Gut microbiome profiles in pancreatic cancer and their interactions with dietary patterns

Molina Montes, Maria Ester (10-09-2022)

Background and aims: Pancreatic cancer (PC) has a high case-fatality rate in Western countries, expected to rise in coming years if no immediate actions are taken. Several studies have pointed to an association between the ...
Polygenic Risk Score in complex diseases

Tomás Dazas, Laureano (09-2018)

Motivation: Plenty genome-wide datasets are produced from complex diseases by traditional GWAS studies, but they are limited. A new approach has emerged in the last decade, the Polygenic Risk Scores (PRS), to combine ...
Refining the genomic landscape of pediatric and young adult aggressive B-cell lymphomas

Colmenero Cobo de Gúzman, Ariadna (12-09-2022)

Aggressive B-cell non-Hodgkin lymphomas in children and young adults (CAYA) include the genetically well-defined Burkitt lymphoma (BL) and diffuse large B-cell lymphoma (DLBCL). Additionally, a group of highly proliferative ...
StP: a web server to predict pathogenesis of non-synonymous single nucleotide polymorphisms in membrane proteins

Reina Fuente, Iker (18-09-2017)

Next-generation sequencing has speed up the process of sequencing a complete human genome, while reducing the cost. Consequently its use is increasing in healthcare in order to identify genetic variations and its association ...
Study of tergal glands morphogenesis through an integrative analysis of genomic data

Ylla Bou, Guillem (09-2014)

About 50% of living species are holometabolan insects. Therefore, unraveling the ori- gin of insect metamorphosis from the hemimetabolan (gradual metamorphosis) to the holometabolan (sudden metamorphosis at the end of ...
Telomere length and Alzheimer's disease endophenotypes: a Mendelian Randomization study

Rodríguez Fernández, Blanca (15-09-2020)

Background: Telomere length (TL) is a putative biomarker of biological aging and aging-related outcomes. Observational studies are limited to conclude whether TL is causally associated with Alzheimer’s Disease (AD) or a ...
The impact and function of C-terminal degrons and protein misfolding in the degradation of truncated proteins

Sánchez Guixé, Mònica (15-09-2020)

Premature Termination Codons (PTCs) are mainly generated after nonsense and frameshift alterations. The Nonsense Mediated Decay (NMD) system detects and degrades mRNAs containing PTCs. However, the efficiency of this ...
The integration of transcriptome and epigenome in the association of mosaic loss of chromosome Y (mLOY) and cancer

Jené Cortada, Aina (15-09-2017)

It has been demonstrated that mosaic loss of chromosome Y (mLOY) is associated with aging and age-related disease such as cancer [1, 2] or Alzheimer's disease [3]. However, the integrate mechanisms of gene expression and ...
Topological Mapping of genetic variations in human Olfactory Receptors

Cierco Jiménez, Ramon (17-09-2018)

The human olfactory system has enormous discriminatory power, with the ability to detect millions of different odorants. The initial recognition of chemical volatiles is performed by the large family of seven-transmembrane ...
Transcriptomic analysis of BRCA1 and BRCA2 carriers

Vilardell Lladó, Marina (01-09-2023)

Most frequently mutations that lead to the development of breast and ovarian cancer are BRCA1 and BRCA2. Blood samples from BRCA1, BRCA2 and non-mutation carriers were extracted for both healthy and cancer-affected ...

Mostrando ítems 55-74 de 78

Buscar en RIUVic

Búsqueda avanzada

Listar

Todo DSpace
Esta colección

Listar Màster Universitari en Anàlisi de Dades Òmiques por título

Listar Màster Universitari en Anàlisi de Dades Òmiques por título

Buscar en RIUVic

Listar

Todo DSpace

Esta colección