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Browsing Articles, congressos, llibres by Author "Olvera, Alex"

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A human immune data-informed vaccine concept elicits strong and broad T-cell specificities associated with HIV-1 control in mice and macaques

Mothe, B.; Hu, Xintao; Llano, Anuska; Rosati, Margherita; Olvera, Alex; Kulkarni, Viraj; Valentin, Antonio; Alicea, Candido; Pilkington, Guy R.; Sardesai, Niranjan J.; Rocafort, Muntsa; Crespo, Manel; Carrillo, Jorge; Marco, Andrés; Mullins, James I.; Dorrell, Lucy; Hanke, Thomas; Clotet, Bonaventura; Pavlakis, George N.; Felber, Barbara; Brander, Christian (BioMed Central, 2015)

Background: None of the HIV T-cell vaccine candidates that have reached advanced clinical testing have been able to induce protective T cell immunity. A major reason for these failures may have been suboptimal T cell immunogen ...
Direct Interrogation of Viral Peptides Presented by the Class I HLA of HIV-Infected T Cells

Yaciuk, Jane C.; Skaley, Matthew; Bardet, Wilfried; Schafer, Danijela Mojsilovic; Cate, Steven; Stewart, Christopher J.; McMurtrey, Curtis; Jackson, Rico Buchli; Olvera, Alex; Cedeño, Samandhy; Plana, Montserrat; Mothe, B.; Brander, Christian; West, John T.; Hildebrand, William (American Socity for Microbiology, 2014)

Identification of CD8+ cytotoxic T lymphocyte (CTL) epitopes has traditionally relied upon testing of overlapping peptide libraries for their reactivity with T cells in vitro. Here, we pursued deep ligand sequencing (DLS) ...
HLA-BM35-PX and HLA-BM35-PY subtype differentiation does not predict observed differences in level of HIV control in a Peruvian MSM cohort

Olvera, Alex; Ganoza, C.; Pérez-Alvarez, Susana; Hildebrand, William; Sánchez, Jorge; Brander, Christian (Lippincott Williams & Wilkins, 2014)
A Novel T-cell Vaccine Eliciting T-cell Specificities Associated with Control of HIV-1 In Humans Is Highly Immunogenic in Mice and Macaques

Mothe, B.; Hu, Xintao; Llano, Anuska; Rosati, Margherita; Olvera, Alex; Kulkarni, Viraj; Valentin, Antonio; Alicea, Candido; Sardesai, Niranjan J.; Rocafort, Muntsa; Crespo, Manel; Carrillo, Jorge; Marco, Andrés; Mullins, James I.; Dorrell, Lucy; Hanke, Thomas; Clotet, Bonaventura; Pavlakis, George N.; Felber, Barbara; Brander, Christian (Mary Ann Liebert, Inc, 2014)
The HLA-C*04:01/KIR2DS4 gene combination and human leukocyte antigen alleles with high population frequency drive rate of HIV disease progression

Olvera, Alex; Pérez-Alvarez, Susana; Ibarrondo, Javier; Ganoza, C.; Lama, Javier R.; Lucchetti, Aldo; Cate, Steven; Hildebrand, William; Bernard, Nicole; Gómez, Guadalupe; Sanchez, Jorge; Brander, Christian (Wolters Kluwer Health, 2015)

Objective: The objective of this study is to identify human leukocyte antigen (HLA) class I and killer-cell immunoglobulin-like receptor (KIR) genotypes associated with different risks for HIV acquisition and HIV disease ...

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Browsing Articles, congressos, llibres by Author "Olvera, Alex"

Browsing Articles, congressos, llibres by Author "Olvera, Alex"

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