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Immune Screening Identifies Novel T Cell Targets Encoded by Antisense Reading Frames of HIV-1

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dc.contributor Universitat de Vic - Universitat Central de Catalunya. Càtedra de la Sida i Malalties Relacionades
dc.contributor.author Berger, Christoph T.
dc.contributor.author Llano, Anuska
dc.contributor.author Carlson, Jonathan M.
dc.contributor.author Brumme, Zabrina L.
dc.contributor.author Brockman, Mark A.
dc.contributor.author Cedeño, Samandhy
dc.contributor.author Harrigan, R.
dc.contributor.author Kaufmann, Daniel E.
dc.contributor.author Heckerman, David
dc.contributor.author Meyerhans, Andreas
dc.contributor.author Brander, Christian
dc.date.accessioned 2015-10-28T09:08:29Z
dc.date.available 2015-10-28T09:08:29Z
dc.date.created 2015
dc.date.issued 2015
dc.identifier.citation Berger, C. T., Llano, A., Carlson, J. M., Brumme, Z. L., Brockman, M. A., Cedeño, S., et al. (2015). Immune screening identifies novel T cell targets encoded by antisense reading frames of HIV-1. Journal of Virology, 89(7), 4015-4019. ca_ES
dc.identifier.issn 1098-5514
dc.identifier.uri http://hdl.handle.net/10854/4320
dc.description.abstract Cytotoxic-T lymphocyte (CTL) responses to epitopes in alternative HIV reading frames have been reported. However, the extent of CTL responses to putative proteins encoded in antisense reading frames is unknown. Using sequence alignments and computational approaches, we here predict five potential antisense HIV proteins and characterize common CTL responses against them. Results suggest that antisense-derived sequences are commonly transcribed and translated and could encode functional proteins that contain important targets of anti-HIV cellular immunity. ca_ES
dc.format application/pdf
dc.format.extent 5 p. ca_ES
dc.language.iso eng ca_ES
dc.publisher American Society for Microbiology ca_ES
dc.rights Tots els drets reservats ca_ES
dc.rights (c) American Society for Microbiology
dc.subject.other Sida -- Tractament ca_ES
dc.subject.other VIH (Virus) ca_ES
dc.title Immune Screening Identifies Novel T Cell Targets Encoded by Antisense Reading Frames of HIV-1 ca_ES
dc.type info:eu-repo/semantics/article ca_ES
dc.identifier.doi https://doi.org/10.1186/s12967-015-0392-5
dc.rights.accessRights info:eu-repo/semantics/openAccess ca_ES
dc.type.version info:eu-repo/publishedVersion ca_ES
dc.indexacio Indexat a WOS/JCR ca_ES
dc.indexacio Indexat a SCOPUS ca_ES

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