The characterization of the small transcriptome reveals a generalized down-regulation both at premanifest
and manifest stages, which brings out the course of Huntington’s disease. Partial Least Squares Discriminant
Analysis ...
Single-cell RNA sequencing (scRNA-seq) is a powerful new method that makes it possible to study gene
expression data at the level of individual cells. Cell type annotation, using a reference sets, is a crucial
step in ...
Background: The field of transcriptomics has developed an exponential growth in the last years thanks to the advances in high throughput RNA sequencing (RNAseq), which is becoming more popular as the cost is decreasing. ...
RNA-sequencing for detecting changes between expression
patterns has emerged as a frequent tool in life sciences stud-
ies. However, it is an under-development tool which still
lacks a standard procedure. This way, many ...
The Piwi-interacting RNA (piRNA) system is an evolutionarily conserved mechanism involved
in the control of transposable elements and maintenance of genomic stability, especially in germ
line cells and in early embryo ...
In the past decades, many breast cancer treatments have been approved. Although an effort has been
done to identify sensitive patients to specific treatments, such as targeted therapies like poly(ADP-ribose)
polymerases ...
About 50% of living species are holometabolan insects. Therefore, unraveling the ori-
gin of insect metamorphosis from the hemimetabolan (gradual metamorphosis) to the
holometabolan (sudden metamorphosis at the end of ...